The organ perfusion angle is wild - if we can reliably extend viability from hours to weeks that fundamentally changes the logistics and economics of transplants. Right now its basically an emergency supply chain problem where distance creates massive constraints. Extended perfusion turns it into a scheduled logistics problem more like standard medical equipment distribution. The Bryan Johnson psilocybin data is interesting but n=1 means its basically anecdote tier. That said the metabolic reset hypothesis is worth exploring - if shrooms are genuinely shifting inflammatory and cortisol baselines thatcould be mechanism rather than placebo. The 3D printed terahertz stuff caught my eye becuase manufacturing constraints have been the bottleneck for that frequency range forever. Being able to print custom optical components instead of hunting for rare materials opens up alot of experimental space.
Banger as usual, will read more about mushrooms now 😌
"Make me a scent that evokes optimism"
Thank you for sharing that video of Christophe Laudamiel abd his recipe for optimism.
That was a great little treat to find at the end of the video I was including anyway.
A great treat, Packy! A Christmas gift of optimism?
https://youtu.be/DwyOvhRIpu4?si=l-L7gSIG9FFIZSQO&t=799
The organ perfusion angle is wild - if we can reliably extend viability from hours to weeks that fundamentally changes the logistics and economics of transplants. Right now its basically an emergency supply chain problem where distance creates massive constraints. Extended perfusion turns it into a scheduled logistics problem more like standard medical equipment distribution. The Bryan Johnson psilocybin data is interesting but n=1 means its basically anecdote tier. That said the metabolic reset hypothesis is worth exploring - if shrooms are genuinely shifting inflammatory and cortisol baselines thatcould be mechanism rather than placebo. The 3D printed terahertz stuff caught my eye becuase manufacturing constraints have been the bottleneck for that frequency range forever. Being able to print custom optical components instead of hunting for rare materials opens up alot of experimental space.